Recombinant humaan CD43 eiwit

SPN is a major sialoglycoprotein found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It may be part of a physiologic ligand-receptor complex involved in T-cell activation. During T-cell activation, this protein is actively removed from the T-cell-APC (antigen-presenting cell) contact site, suggesting a negative regulatory role in adaptive immune response. Recombinant human SPN protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Leukosialin precursor, CD43, GALGP, GPL115, LSN

E.coli

Human

His-Tag

SDS-PAGE

1 mg/mL (determined by absorbance at 280 nm)

> 85% by SDS-PAGE

25.8 kDa (257aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

CD43, leukosialin precursor, CD43, GALGP, GPL115, LSN, ATGP2310-10 µg, ATGP2310-20 µg, ATGP2310-50 µg, ATGP2310-100 µg, ATGP2310-250 µg, ATGP2310-500 µg, ATGP2310-1 mg, ATGP2310-10, ATGP2310-20, ATGP2310-50, ATGP2310-100, ATGP2310-250, ATGP2310-500, ATGP2310-1

Park, H.J., et al. (2012) Am. J. Surg. Pathol. 36 (8), 1150-1157; ; Balikova, A., et al. (2012) Int. J. Oncol. 41 (1), 299-309

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol

Stem cell

NP_003114.1

P16150

Human

STTAVQT PTSGEPLVST SEPLSSKMYT TSITSDPKAD STGDQTSALP PSTSINEGSP LWTSIGASTG SPLPEPTTYQ EVSIKMSSVP QETPHATSHP AVPITANSLG SHTVTGGTIT TNSPETSSRT SGAPVTTAAS SLETSRGTSG PPLTMATVSL ETSKGTSGPP VTMATDSLET STGTTGPPVT MTTGSLEPSS GASGPQVSSV KLSTMMSPTT STNASTVPFR NPDENSR