Recombinant humaan CD66e/CEACAM5-eiwit

CEACAM5, as known as carcinoembryonic antigen-related cell adhesion molecule 5, is the large CEACAM subfamily of immunoglobulin superfamily. This protein can mediate cell to cell adhesion through homotypic and heterotypic interactions. It is restricted to the apical face of intestinal epithelial cells in the adult but is more diffuse during embryonic development and in tumors. Also, it is upregulated in a wide variety of human tumors and is a commonly used cancer marker. Recombinant human CEACAM5, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Carcinoembryonic antigen-related cell adhesion molecule 5, CEACAM5, CD66e, CEA, CEA cell adhesion molecule 5

Baculovirus

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by BCA assay)

< 1 EU per 1ug of protein (determined by LAL method)

> 95% by SDS-PAGE

72.3 kDa (659aa)

CEACAM5, CD66e, ATGP3546-10 µg, ATGP3546-20 µg, ATGP3546-50 µg, ATGP3546-100 µg, ATGP3546-250 µg, ATGP3546-500 µg, ATGP3546-1 mg, ATGP3546-10, ATGP3546-20, ATGP3546-50, ATGP3546-100, ATGP3546-250, ATGP3546-500, ATGP3546-1

Filiberti R., et al, (2013) Med. Oncol. 30:543.; ; Jurgensmeier JM., et al, (2013) Br. J. Cancer 108:1316-1323.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Cancer

NP_004354

P06731

Human

Lys35