Recombinant humaan CD71/TFRC-eiwit

TFRC, also known as transferrin receptor protein 1, is a transmembrane glycoprotein composed of two disulfide-linked monomers joined by two disulfide bonds. It acts as cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. This protein is necessary for development of erythrocytes and the nervous system. And it is positively regulates T and B cell proliferation through iron uptake. Recombinant human TFRC protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

TRFR, Transferrin receptor protein 1 isoform 1, Transferrin receptor protein 1, TR, TFRC, TFR-1, TFR1, TFR 1, TFR, T9, p90, IMD46, CD71, CD 71

Baculovirus

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 90% by SDS-PAGE

74.9 kDa (669aa)

TRFR, Transferrin receptor protein 1 isoform 1, Transferrin receptor protein 1, TR, TFRC, TFR-1, TFR1, TFR 1, TFR, T9, p90, IMD46, CD71, CD 71, ATGP3825-10 µg, ATGP3825-20 µg, ATGP3825-50 µg, ATGP3825-100 µg, ATGP3825-250 µg, ATGP3825-500 µg, ATGP3825-1 mg, ATGP3825-010, ATGP3825-020, ATGP3825-050, ATGP3825-100, ATGP3825-250, ATGP3825-500, ATGP3825-01M

Laube F., et al, (2017) Anticancer Res. 37:3001-3007.; ; Zhou JH., et al, (2017) J Neurosci. 37:11335-11352.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Cardiovascular

NP_001121620

P02786

Human

Ala

ADPLAGTESP VREEPGEDFP AARRLYWDDL KRKLSEKLDS TDFTGTIKLL NENSYVPREA GSQKDENLAL YVENQFREFK LSKVWRDQHF VKIQVKDSAQ NSVIIVDKNG RLVYLVENPG GYVAYSKAAT VTGKLVHANF GTKKDFEDLY TPVNGSIVIV RAGKITFAEK VANAESLNAI GVLIYMDQTK FPIVNAELSF FGHAHLGTGD PYTPGFPSFN HTQFPPSRSS GLPNIPVQTI SRAAAEKLFG NMEGDCPSDW KTDSTCRMVT SESKNVKLTV SNVLKEIKIL NIFGVIKGFV EPDHYVVVGA QRDAWGPGAA KSGVGTALLL KLAQMFSDMV LKDGFQPSRS IIFASWSAGD FGSVGATEWL EGYLSSLHLK AFTYINLDKA VLGTSNFKVS ASPLLYTLIE KTMQNVKHPV TGQFLYQDSN WASKVEKLTL DNAAFPFLAY SGIPAVSFCF CEDTDYPYLG TTMDTYKELI ERIPELNKVA RAAAEVAGQF VIKLTHDVEL NLDYERYNSQ LLSFVRDLNQ YRADIKEMGL SLQWLYSARG DFFRATSRLT TDFGNAEKTD RFVMKKLNDR VMRVEYHFLS PYVSPKESPF RHVFWGSGSH TLPALLENLK LRKQNNGAFN ETLFRNQLAL ATWTIQGAAN ALSGDVWDID NEFHHHHHH