Recombinant humaan CD79A-eiwit

CD79A, also known as B-cell antigen receptor complex-associated protein alpha chain isoform 1, is a membrane-spanning, signal-transducing components of the B-cell receptor. It plays multiple and diverse roles in B cell development and function. It can be a cause of agammaglobulinemia. It is upregulated on MDSCs and activated in response to soluble factors secreted by tumor cells. It plays a functional role in the tumor promoting effects of myeloid cells, and may represent a novel target for cancer therapy. Recombinant human CD79A, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

B-cell antigen receptor complex-associated protein alpha chain isoform 1, CD79A, IGA, MB-1

Baculovirus

Human

His-Tag

SDS-PAGE

1 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 95% by SDS-PAGE

13.6 kDa (119aa)

CD79A, B-cell antigen receptor complex-associated protein alpha chain isoform 1, CD79A, IGA, MB-1, ATGP3655-10 µg, ATGP3655-20 µg, ATGP3655-50 µg, ATGP3655-100 µg, ATGP3655-250 µg, ATGP3655-500 µg, ATGP3655-1 mg, ATGP3655-10, ATGP3655-20, ATGP3655-50, ATGP3655-100, ATGP3655-250, ATGP3655-500, ATGP3655-1

Wang Y., et al. (2002) Am J Med Genet. 108:333-336.; ; Luger D., et al. (2013) PLoS One. 8:e76115.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Immunology

NP_001774

P11912

Human

Leu33