Recombinant humaan CD79B-eiwit

CD79B, as known as B-cell antigen receptor complex-associated protein beta chain isoform 1, is B-cell-specific glycoprotein B29. It is a single-pass type 1 membrane protein containing one Ig-like V-type domain and one ITAM domain. This protein is required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) . CD79A and B proteins are required for BCR-meditated signaling and consequently for the development and activation of B lineage cells. Recombinant human CD79B, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

B-cell antigen receptor complex-associated protein beta chain isoform 1, CD79B, AGM6, B29, IGB

Baculovirus

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 90% by SDS-PAGE

16.3 kDa (140aa)

CD79B, B-cell antigen receptor complex-associated protein beta chain isoform 1, CD79B, AGM6, B29, IGB, ATGP3542-10 µg, ATGP3542-20 µg, ATGP3542-50 µg, ATGP3542-100 µg, ATGP3542-250 µg, ATGP3542-500 µg, ATGP3542-1 mg, ATGP3542-10, ATGP3542-20, ATGP3542-50, ATGP3542-100, ATGP3542-250, ATGP3542-500, ATGP3542-1

Jahn L., et al, (2015) Blood 125:949-958.; ; Yamada S., et al, (2015) Leuk. Lymphoma 56:2141-2145.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Immunology

NP_000617

P40259

Human

Ala

ADPARSEDRY RNPKGSACSR IWQSPRFIAR KRGFTVKMHC YMNSASGNVS WLWKQEMDEN PQQLKLEKGR MEESQNESLA TLTIQGIRFE DNGIYFCQQK CNNTSEVYQG CGTELRVMGF STLAQLKQRN TLKDHHHHHH