Recombinant humaan CD8 bèta-eiwit

CD8B, also known as T-cell surface glycoprotein CD8 beta chain isoform 5, is a cell surface transmembrane glycoprotein. This protein serves as a co-receptor for the T cell receptor (TCR) . It found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. CD8 forms a dimer, consisting of a pair of CD8 chains. The most common form of CD8 is composed of a CD8-alpha and CD8-beta chain. Both members of the immunoglobulin superfamily with an immunoglobulin variable (IgV) -like extracellular domain connected to the membrane by a thin stalk, and an intracellular tail. Recombinant human CD8B, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

T-cell surface glycoprotein CD8 beta chain isoform 5, CD8B, CD8B1, LEU2, LY3, LYT3, P37

Baculovirus

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 85% by SDS-PAGE

17.8 kDa (158aa)

CD8 b, T-cell surface glycoprotein CD8 beta chain isoform 5, CD8B, CD8B1, LEU2, LY3, LYT3, P37, ATGP3757-10 µg, ATGP3757-20 µg, ATGP3757-50 µg, ATGP3757-100 µg, ATGP3757-250 µg, ATGP3757-500 µg, ATGP3757-1 mg, ATGP3757-10, ATGP3757-20, ATGP3757-50, ATGP3757-100, ATGP3757-250, ATGP3757-500, ATGP3757-1

Johnson P. (1987) Immunogenetics 26:174-177.; ; Terry LA. et al., (1990) Tissue Antigens 35:82-91.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Immunology

NP_004922.1

P10966

Human

Ala

LQQTPAY IKVQTNKMVM LSCEAKISLS NMRIYWLRQR QAPSSDSHHE FLALWDSAKG TIHGEEVEQE KIAVFRDASR FILNLTSVKP EDSGIYFCMI VGSPELTFGK GTQLSVVDFL PTTAQPTKKS TLKKRVCRLP RPETQKGPLC SP