Recombinant humaan CD81-eiwit

CD81, also known as CD81 antigen isoform 1, belongs to the tetraspanin family. It interacts directly with immunoglobulin superfamily member 8 (IGSF8, CD316) and CD36. In B cells, it is part of a complex with CD21, CD19 and Leu13. This complex reduces the threshold for B cell activation through B cell receptors by linking Ag specific recognition and CD21 mediator recognition. On T cells it associates with CD4 and CD8 and provides a costimulatory signal with CD3. Recombinant human CD81, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

CD81 antigen isoform 1, CD81, CVID6, S5.7, TAPA1, TSPAN28

Baculovirus

Human

HIgG-His-Tag

SDS-PAGE

0.5 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 95% by SDS-PAGE

37 kDa (331aa)

CD81, CD81 antigen isoform 1, CD81, CVID6, S5.7, TAPA1, TSPAN28, ATGP3661-10 µg, ATGP3661-20 µg, ATGP3661-50 µg, ATGP3661-100 µg, ATGP3661-250 µg, ATGP3661-500 µg, ATGP3661-1 mg, ATGP3661-10, ATGP3661-20, ATGP3661-50, ATGP3661-100, ATGP3661-250, ATGP3661-500, ATGP3661-1

Charrin S., et al. (2014) J. Cell. Sci. 127:3641-3648.; ; Oren, R., et al. (1990) Mol. Cell. Biol. 10:4007-4015.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Immunology

NP_004347.1

P60033

Human

Ala

FVNKDQI AKDVKQFYDQ ALQQAVVDDD ANNAKAVVKT FHETLDCCGS STLTALTTSV LKNNLCPSGS NIISNLFKED CHQKIDDLFS GK