Recombinant humaan CD9-eiwit

CD9, also known as TSPAN-29, is a member of tetraspanin family. It is found on the surface of exosomes. It can modulate cell adhesion and migration and also trigger platelet activation and aggregation. In addition, the protein appears to promote muscle cell fusion and support myotube maintenance. It seems CD9 has a varying role in different types of cancers. The over expression of CD9 was shown to decrease metastasis in certain types of melanoma, breast, lung, pancreas and colon carcinomas. However in other studies, CD9 has been shown to increase migration or be highly expressed in metastatic cancers in various cell lines such as lung cancer, scirrhous-type gastric cancer, hepatocellular carcinoma, acute lymphoblastic leukemia and breast cancer. Recombinant human CD9, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

CD9 antigen, BTCC-1, DRAP-27, MIC3, MRP-1, TSPAN-29, TSPAN29, BA2,5H9 antigen, Cell growth-inhibiting gene 2 protein, Leukocyte antigen MIC3, p24, CD9 antigen isoform1

Baculovirus

Human

HIgG-His-Tag

SDS-PAGE

1 mg/mL (determined by Absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 95% by SDS - PAGE

36.9kDa (326aa)

ATGP4006-10 µg, ATGP4006-50 µg, ATGP4006-100 µg, ATGP4006-200ug, ATGP4006-250 µg, ATGP4006-500 µg, ATGP4006-1 mg, ATGP4006-10 µg, ATGP4006-20 µg, ATGP4006-50 µg, ATGP4006-100 µg, ATGP4006-250 µg, ATGP4006-500 µg, ATGP4006-1 mg, ATGP4006-10, ATGP4006-20, ATGP4006-50, ATGP4006-100, ATGP4006-250, ATGP4006-500, ATGP4006-1

Sara J, Eileen M, et al. (2001) . Thromb Haemost. 85 (1) :134-141.; ; Rubinstein E, Billard M, et al. (1993) . Thrombosis Research. 71 (5) : 377–383.; ; Blake DJ, Martiszus JD, et al. (2018) . Cytokine. 111: 567–570.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid. In Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol.

Cardiovascular

NP_001760.1

P21926

Human

Ala

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