Recombinant humaan CD94/KLRD1-eiwit

KLRD1, also known as natural killer cells antigen CD94 isoform 1, is expressed on the surface of natural killer cells in the innate immune system. It plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. This protein can form disulfide-bonded heterodimer with NKG2 family members. CD94 and NKG2 complex interacts with Human Leukocyte Antigen (HLA) -E on target cells on the surface of natural killer cells. Recombinant human KLRD1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Killer cell lectin like receptor D1, Natural killer cells antigen CD94, KP43, Killer cell lectin-like receptor subfamily D member 1, NK cell receptor

Baculovirus

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 95% by SDS-PAGE

18.2 kDa (157aa)

CD94, Natural killer cells antigen CD94 isoform 1, KLRD1, CD94, ATGP3669-10 µg, ATGP3669-20 µg, ATGP3669-50 µg, ATGP3669-100 µg, ATGP3669-250 µg, ATGP3669-500 µg, ATGP3669-1 mg, ATGP3669-10, ATGP3669-20, ATGP3669-50, ATGP3669-100, ATGP3669-250, ATGP3669-500, ATGP3669-1

Phillips JH., et al, (1996) Immunity 5:163-172.; ; Brooks AG., et al, (1997) J. Exp. Med. 185:795-800.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Immunology

NP_002253

Q13241

Human

Ala

ADPKNSFTKL SIEPAFTPGP NIELQKDSDC CSCQEKWVGY RCNCYFISSE QKTWNESRHL CASQKSSLLQ LQNTDELDFM SSSQQFYWIG LSYSEEHTAW LWENGSALSQ YLFPSFETFN TKNCIAYNPN GNALDESCED KNRYICKQQL IHHHHHH