Recombinant humaan CDCP1-eiwit

CDCP1, also known as CUB domain-containing protein 1 isoform 1, is a transmembrane protein containing three extracellular CUB domains. This protein is involved in cell adhesion and cell matrix association. Also, CDCP1 may play a role in the regulation of anchorage versus migration or proliferation versus differentiation via its phosphorylation and may be a novel marker for leukemia diagnosis and for immature hematopoietic stem cell subsets. The extracellular region of human CDCP1 shares amino acid identity sequence with that of the mouse protein. Recombinant human CDCP1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

CDCP1, CD318, SIMA135, TRASK, Membrane glycoprotein gp140

Baculovirus

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 90% by SDS-PAGE

72.8 kDa (646aa)

CDCP1, CDCP1, CD318, SIMA135, TRASK, Membrane glycoprotein gp140, ATGP3306-10 µg, ATGP3306-20 µg, ATGP3306-50 µg, ATGP3306-100 µg, ATGP3306-250 µg, ATGP3306-500 µg, ATGP3306-1 mg, ATGP3306-10, ATGP3306-20, ATGP3306-50, ATGP3306-100, ATGP3306-250, ATGP3306-500, ATGP3306-1

Miura S., et al. (2014) Exp. Cell Res. 321:209-218.; ; Uekita., et al. (2013) Cancer Sci. 104:865-870.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Cancer

NP_073753.3

Q9H5V8

Human

Phe30