Recombinant humaan CDK16-eiwit

Cyclin-dependent kinase 16 isoform 1, also known as CDK16, belong to the CDK family of serine/threonine protein kinases. These proteins have a core kinase domain flanked by unique amino- and carboxy-terminal domains. CDK proteins are known to regulate the cell cycle. CDK16, which is expressed primarily in mammalian brain, interacts with a variety of proteins, and is thought to be part of a multiple signal transduction cascade. Recombinant human CDK16 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Cyclin-dependent kinase 16 isoform 1, Cyclin-dependent kinase 16 isoform 1, PCTAIRE, PCTAIRE1, PCTGAIRE, PCTK1

E.coli

Human

His-Tag

SDS-PAGE

1 mg/mL (determined by Bradford assay)

> 95% by SDS-PAGE

41.1 kDa (362aa) confirmed by MALDI-TOF

CDK16, Cyclin-dependent kinase 16 isoform 1, Cyclin-dependent kinase 16 isoform 1, PCTAIRE, PCTAIRE1, PCTGAIRE, PCTK1, ATGP2423-10 µg, ATGP2423-20 µg, ATGP2423-50 µg, ATGP2423-100 µg, ATGP2423-250 µg, ATGP2423-500 µg, ATGP2423-1 mg, ATGP2423-10, ATGP2423-20, ATGP2423-50, ATGP2423-100, ATGP2423-250, ATGP2423-500, ATGP2423-1

Cheng K., et al. (2002) J Biol Chem. 277:31988-31993.; ; Meyerson M., et al. (1992) EMBO J. 118:2909-2917.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol

Signal Transduction

NP_006192

Q00536

Human

GFGKLET YIKLDKLGEG TYATVYKGKS KLTDNLVALK EIRLEHEEGA PCTAIREVSL LKDLKHANIV TLHDIIHTEK SLTLVFEYLD KDLKQYLDDC GNIINMHNVK LFLFQLLRGL AYCHRQKVLH RDLKPQNLLI NERGELKLAD FGLARAKSIP TKTYSNEVVT LWYRPPDILL GSTDYSTQID MWGVGCIFYE MATGRPLFPG STVEEQLHFI FRILGTPTEE TWPGILSNEE FKTYNYPKYR AEALLSHAPR LDSDGADLLT KLLQFEGRNR ISAEDAMKHP FFLSLGERIH KLPDTTSIFA LKEIQLQKEA SLRSSSMPDS GRPAFRVVDT EF