Recombinant humaan CDK5RAP3-eiwit

CDK5RAP3 also known as CDK5 regulatory subunit-associated protein 3. This protein is potential regulator of CDK5 activity via its interaction with CDK5R. Neuronal CDC2-like kinase, which is involved in the regulation of neuronal differentiation, is composed of a catalytic subunit, CDK5, nad an activating subunit, p25NCK5A. CDK5RAP3 binds to p25NCK5A and therefore may be involved in neuronal differentiation. Recombinant human CDK5RAP3, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

CDK5 regulatory subunit-associated protein 3 isoform b, C53, HSF-27, IC53, LZAP, MST016, OK/SW-cl.114, PP1553

E.coli

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

59kDa (526aa)

CDK5RAP3, CDK5 regulatory subunit-associated protein 3 isoform b, C53, HSF-27, IC53, LZAP, MST016, OK/SW-cl.114, PP1553, ATGP3070-10 µg, ATGP3070-20 µg, ATGP3070-50 µg, ATGP3070-100 µg, ATGP3070-250 µg, ATGP3070-500 µg, ATGP3070-1 mg, ATGP3070-10, ATGP3070-20, ATGP3070-50, ATGP3070-100, ATGP3070-250, ATGP3070-500, ATGP3070-1

Kim S., et al. (2014) PLoS One. Jan 22; ;9 (1) :e87016.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 20% glycerol, 1mM DTT

Cell Cycle

NP_788276

Q96JB5

Human

MGSSHHHHHH SSGLVPRGSH MEDHQHVPID IQTSKLLDWL VDRRHCSLKW QSLVLTIREK INAAIQDMPE SEEIAQLLSG SYIHYFHCLR ILDLLKGTEA STKNIFGRYS SQRMKDWQEI IALYEKDNTY LVELSSLLVR NVNYEIPSLK KQIAKCQQLQ QEYSRKEEEC QAGAAEMREQ FYHSCKQYGI TGENVRGELL ALVKDLPSQL AEIGAAAQQS LGEAIDVYQA SVGFVCESPT EQVLPMLRFV QKRGNSTVYE WRTGTEPSVV ERPHLEELPE QVAEDAIDWG DFGVEAVSEG TDSGISAEAA GIDWGIFPES DSKDPGGDGI DWGDDAVALQ ITVLEAGTQA PEGVARGPDA LTLLEYTETR NQFLDELMEL EIFLAQRAVE LSEEADVLSV SQFQLAPAIL QGQTKEKMVT MVSVLEDLIG KLTSLQLQHL FMILASPRYV DRVTEFLQQK LKQSQLLALK KELMVQKQQE ALEEQAALEP KLDLLLEKTK ELQKLIEADI SKRYSGRPVN LMGTSL