Recombinant humaan CEACAM21-eiwit

CEACAM21 is a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. Recombinant human CEACAM21 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Carcinoembryonic antigen-related cell adhesion molecule 21, R29124_1, CEA cell adhesion molecule 21

E.coli

Human

His-Tag

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

25 kDa (229aa)

CEACAM21, Carcinoembryonic antigen-related cell adhesion molecule 21, CEACAM3, R29124_1, ATGP2254-10 µg, ATGP2254-20 µg, ATGP2254-50 µg, ATGP2254-100 µg, ATGP2254-250 µg, ATGP2254-500 µg, ATGP2254-1 mg, ATGP2254-10, ATGP2254-20, ATGP2254-50, ATGP2254-100, ATGP2254-250, ATGP2254-500, ATGP2254-1

Schmitter T, Agerer F, et al. (2004) . J Exp Med. 199 (1) :35-46.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Immunology

NP_001091976

Q3KPI0

Human

MGSSHHHHHH SSGLVPRGSH MGSWLFIASA PFEVAEGENV HLSVVYLPEN LYSYGWYKGK TVEPNQLIAA YVIDTHVRTP GPAYSGRETI SPSGDLHFQN VTLEDTGYYN LQVTYRNSQI EQASHHLRVY ESVAQPSIQA SSTTVTEKGS VVLTCHTNNT GTSFQWIFNN QRLQVTKRMK LSWFNHVLTI DPIRQEDAGE YQCEVSNPVS SNRSDPLKLT VKSDDNTLG