Recombinant humaan CEND1-eiwit

CEND1, as known as BM88, is a neuron-specific protein. It participates in cell cycle control and neuronal differentiation mechanisms during neonatal SVZ neurogenesis and becomes crucial for the transition from neuroblasts to mature neurons when reaching high levels. The similar protein in pig enhances neuroblastoma cell differentiation in vitro and may be involved in neuronal differentiation in vivo. Recombinant human CEND1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Cell cycle exit and neuronal differentiation protein 1, Cell cycle exit and neuronal differentiation protein 1, BM88

E.coli

Human

His-Tag

SDS-PAGE

1 mg/mL (determined by BCA assay)

> 85% by SDS-PAGE

15kDa (148aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

CEND1, Cell cycle exit and neuronal differentiation protein 1, Cell cycle exit and neuronal differentiation protein 1, BM88, ATGP2494-10 µg, ATGP2494-20 µg, ATGP2494-50 µg, ATGP2494-100 µg, ATGP2494-250 µg, ATGP2494-500 µg, ATGP2494-1 mg, ATGP2494-10, ATGP2494-20, ATGP2494-50, ATGP2494-100, ATGP2494-250, ATGP2494-500, ATGP2494-1

Makri G. et al. (2010) Stem Cells. 28:127-139; ; Katsimpardi L. et al. (2008) Stem Cells. 26:1796-1807.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Neuroscience

NP_057648

Q8N111

Human

MESRGKS ASSPKPDTKV PQVTTEAKVP PAADGKAPLT KPSKKEAPAE KQQPPAAPTT APAKKTSAKA DPALLNNHSN LKPAPTVPSS PDATPEPKGP GDGAEEDEAA SGGPGGRGPW SCENFNPL