Recombinant humaan CENPP-eiwit

Centromere protein P, also known as CENPP, is component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. This protein may be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Recombinant human CENPP protein, fused to His-tag at N-terminus, was expressed in E. coli.

Centromere protein P, CENP-P, RP11-19J3.3

E.coli

Human

His-Tag

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

35.3 kDa (308aa)

CENPP, Centromere protein P, CENP-P, RP11-19J3.3, ATGP2448-10 µg, ATGP2448-20 µg, ATGP2448-50 µg, ATGP2448-100 µg, ATGP2448-250 µg, ATGP2448-500 µg, ATGP2448-1 mg, ATGP2448-10, ATGP2448-20, ATGP2448-50, ATGP2448-100, ATGP2448-250, ATGP2448-500, ATGP2448-1

Okada M., et al. (2006) Nat. Cell Biol. 8:446-457; ; Foltz D.R., et al. (2006) Nat. Cell Biol. 8:458-469

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Epigenomics (Transcription & Translation)

NP_001012267

Q6IPU0

Human

MDAELAEVRA LQAEIAALRR ACEDPPAPWE EKSRVQKSFQ AIHQFNLEGW KSSKDLKNQL GHLESELSFL STLTGINIRN HSKQTEDLTS TEMTEKSIRK VLQRHRLSGN CHMVTFQLEF QILEIQNKER LSSAVTDLNI IMEPTECSEL SEFVSRAEER KDLFMFFRSL HFFVEWFEYR KRTFKHLKEK YPDAVYLSEG PSSCSMGIRS ASRPGFELVI VWRIQIDEDG KVFPKLDLLT KVPQRALELD KNRAIETAPL SFRTLVGLLG IEAALESLIK SLCAEENN