Recombinant humaan chitinase 3-achtig 2/CHI3L2-eiwit

CHI3L2, also known as chitinase-3-like protein 2, belongs to chitinase protein family. It is secreted by synovial fibroblasts, chondrocytes, and TGFb/IL4 stimulated monocyte derived macrophages. It has been proposed as a potential biomarker for osteoarthritis. Recombinant human CHI3L2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

CHI3L2, CHIL2, YKL-39, YKL39

Baculovirus

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 90% by SDS-PAGE

41.9 kDa (372aa)

Chitinase3-like2, CHI3L2, CHIL2, YKL-39, YKL39, ATGP3294-10 µg, ATGP3294-20 µg, ATGP3294-50 µg, ATGP3294-100 µg, ATGP3294-250 µg, ATGP3294-500 µg, ATGP3294-1 mg, ATGP3294-10, ATGP3294-20, ATGP3294-50, ATGP3294-100, ATGP3294-250, ATGP3294-500, ATGP3294-1

Hu B., et al. (1996) J. Biol. Chem. 271:19415-19420.; ; Gratchev A., et al. (2008) Biomarker Insights. 3:39-44.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Stem cell

NP_003991

Q15782

Human

Tyr27

YKLVCYFTNW SQDRQEPGKF TPENIDPFLC SHLIYSFASI ENNKVIIKDK SEVMLYQTIN SLKTKNPKLK ILLSIGGYLF GSKGFHPMVD SSTSRLEFIN SIILFLRNHN FDGLDVSWIY PDQKENTHFT VLIHELAEAF QKDFTKSTKE RLLLTAGVSA GRQMIDNSYQ VEKLAKDLDF INLLSFDFHG SWEKPLITGH NSPLSKGWQD RGPSSYYNVE YAVGYWIHKG MPSEKVVMGI PTYGHSFTLA SAETTVGAPA SGPGAAGPIT ESSGFLAYYE ICQFLKGAKI TRLQDQQVPY AVKGNQWVGY DDVKSMETKV QFLKNLNLGG AMIWSIDMDD FTGKSCNQGP YPLVQAVKRS LGSLLEHHHH HH