Recombinant humaan choriongonadotrofine subeenheid bèta/CGB-eiwit

CGB3, also known as choriogonadotropin subunit beta, is a member of the glycoprotein hormone beta chain family and encodes the beta 3 subunit of chorionic gonadotropin (CG) . It stimulates the expression of GCM1 target genes, including the fusogenic protein syncytin-1, to promote placental cell fusion. It synthesized in large quantities by the developing placenta, reaching peak concentrations in maternal blood during the late first trimester and early midtrimester of pregnancy. It is expressed exclusively by trophoblasts. It is an important biomarker in pregnancy and oncology, where it is routinely detected and quantified by specific immunoassays. Recombinant human CGB3, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Choriogonadotropin subunit beta, CGB3, CGB, CGB5, CGB7, CGB8, hCGB

Baculovirus

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by BCA assay)

< 1 EU per 1ug of protein (determined by LAL method)

> 85% by SDS-PAGE

16.6 kDa (154aa)

CGB3, Choriogonadotropin subunit beta, CGB3, CGB, CGB5, CGB7, CGB8, hCGB, ATGP3529-10 µg, ATGP3529-20 µg, ATGP3529-50 µg, ATGP3529-100 µg, ATGP3529-250 µg, ATGP3529-500 µg, ATGP3529-1 mg, ATGP3529-10, ATGP3529-20, ATGP3529-50, ATGP3529-100, ATGP3529-250, ATGP3529-500, ATGP3529-1

Cheong ML., et al. (2015) Mol Cell Biol. 36:197-209.; ; Gregor CR., et al. (2011) J Biol Chem. 286:25016-25026.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 20% glycerol

Signal Transduction

NP_000728

P0DN86

Human

Ala

SKEPLRP RCRPINATLA VEKEGCPVCI TVNTTICAGY CPTMTRVLQG VLPALPQVVC NYRDVRFESI RLPGCPRGVN PVVSYAVALS CQCALCRRST TDCGGPKDHP LTCDDPRFQD SSSSKAPPPS LPSPSRLPGP SDTPILPQ