Recombinant humaan CHRNA3-eiwit

CHRNA3 also known as neuronal acetylcholine receptor subunit alpha-3 isoform 1 is a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. CHRNA3 is a ligand-gated ion channel that likely plays a role in neurotransmission. CHRNA3 have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described. Recombinant human CHRNA3 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Neuronal acetylcholine receptor subunit alpha-3 isoform 1, LNCR2, NACHRA3, PAOD2

E.coli

Human

His-Tag

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 80% by SDS-PAGE

27 kDa (232aa)

CHRNA3, Neuronal acetylcholine receptor subunit alpha-3 isoform 1, LNCR2, NACHRA3, PAOD2, ATGP3106-10 µg, ATGP3106-20 µg, ATGP3106-50 µg, ATGP3106-100 µg, ATGP3106-250 µg, ATGP3106-500 µg, ATGP3106-1 mg, ATGP3106-10, ATGP3106-20, ATGP3106-50, ATGP3106-100, ATGP3106-250, ATGP3106-500, ATGP3106-1

Criado JR., et al. (2014) Twin Res Him Genet. 17 (2) :80-8.; ; Rempel N., et al. (1998) Hum. Genet. 103:645-653.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Neuroscience

NP_000734

P32297

Human

SEAEHRL FERLFEDYNE IIRPVANVSD PVIIHFEVSM SQLVKVDEVN QIMETNLWLK QIWNDYKLKW NPSDYGGAEF MRVPAQKIWK PDIVLYNNAV GDFQVDDKTK ALLKYTGEVT WIPPAIFKSS CKIDVTYFPF DYQNCTMKFG SWSYDKAKID LVLIGSSMNL KDYWESGEWA IIKAPGYKHD IKYNCCEEIY PDITYSLYIR RL