Recombinant humaan CINP-eiwit

CINP, also known as Cyclin-dependent kinase 2-interacting protein, belongs to the CINP family. This protein interacts with the components of the replication complex and 2 kinases, CDK2 and CDC7, thereby providing a functional and physical link between CDK2 and CDC7 during firing of the origins of replication. Recombinant human CINP protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Cyclin-dependent kinase 2-interacting protein, CDK2-interacting protein

E.coli

Human

His-Tag

SDS-PAGE

1 mg/mL (determined by Bradford assay)

> 95% by SDS-PAGE

26.4 kDa (232aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

CINP, Cyclin-dependent kinase 2-interacting protein, CDK2-interacting protein, ATGP1118-10 µg, ATGP1118-20 µg, ATGP1118-50 µg, ATGP1118-100 µg, ATGP1118-250 µg, ATGP1118-500 µg, ATGP1118-1 mg, ATGP1118-10, ATGP1118-20, ATGP1118-50, ATGP1118-100, ATGP1118-250, ATGP1118-500, ATGP1118-1

Grishina I., et al. (2005) Cell Cycle. 4:1120-1126; ; Lovejoy C.A., et al. (2009) Proc. Natl. Acad. Sci. u.S.A. 106:19304-19309

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT

Cell Cycle

NP_116019

Q9BW66

Human

MGSSHHHHHH SSGLVPRGSH MEAKTLGTVT PRKPVLSVSA RKIKDNAADW HNLILKWETL NDAGFTTANN IANLKISLLN KDKIELDSSS PASKENEEKV CLEYNEELEK LCEELQATLD GLTKIQVKME KLSSTTKGIC ELENYHYGEE SKRPPLFHTW PTTHFYEVSH KLLEMYRKEL LLKRTVAKEL AHTGDPDLTL SYLSMWLHQP YVESDSRLHL ESMLLETGHR AL