Recombinant humaan CLEC-2/CLEC1B eiwit

CLEC1B, as known as C-type lectin domain family 1 member B, is a type 2 transmembrane glycoprotein and member of the C-type lectin-like family of receptors. This protein is expressed preferentially in liver, and is also detected in myeloid cells, platelets, and megakaryocytes. It has been reported that CLEC2/CLEC1B meditates powerful platelet aggregation by binding to the snake venom protein, rhodocytin and the molecule podoplanin. Recombinant human CLEC1B, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

C-type lectin domain family 1 member B, CLEC2, CLEC-2

Baculovirus

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 90% by SDS-PAGE

21.8 kDa (184aa)

810061I13Rik, CLEC1B, CLEC2, CLEC-2, CLEC2B, C-type lectin domain family 1 member B, C-type lectin domain family 1 member B isoform a, PRO1384, ATGP3436-10 µg, ATGP3436-20 µg, ATGP3436-50 µg, ATGP3436-100 µg, ATGP3436-250 µg, ATGP3436-500 µg, ATGP3436-1 mg, ATGP3436-010, ATGP3436-020, ATGP3436-050, ATGP3436-100, ATGP3436-250, ATGP3436-500, ATGP3436-01M

Chaipan C., et al, (2006) J. Virol. 80:8951-8960.; ; Colonna M., et al, (2000) Eur. J. Immunol. 30:697-704.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Immunology

NP_057593

Q9P126

Human

Ala

ADPSVMQRNY LQGENENRTG TLQQLAKRFC QYVVKQSELK GTFKGHKCSP CDTNWRYYGD SCYGFFRHNL TWEESKQYCT DMNATLLKID NRNIVEYIKA RTHLIRWVGL SRQKSNEVWK WEDGSVISEN MFEFLEDGKG NMNCAYFHNG KMHPTFCENK HYLMCERKAG MTKVDQLPHH HHHH