Recombinant humaan CMG-2-eiwit

ANTXR2 is called anthrax toxin receptor 2 because it allows the toxin that causes anthrax to attach to cells and trigger disease. This protein is involved in the formation of tiny blood vessels (capillaries) . It is also important for maintaining the structure of basement membranes, which are thin, sheet-like structures that separate and support cells in many tissues. Recombinant human ANTXR2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Anthrax toxin receptor 2, CMG-2, m CMG2, HFS, ISH, JHF

E.coli

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

33.0 kDa (307aa) confirmed by MALDI-TOF

CMG2, ATGP2762-10 µg, ATGP2762-20 µg, ATGP2762-50 µg, ATGP2762-100 µg, ATGP2762-250 µg, ATGP2762-500 µg, ATGP2762-1 mg, ATGP2762-10, ATGP2762-20, ATGP2762-50, ATGP2762-100, ATGP2762-250, ATGP2762-500, ATGP2762-1

Scobie HM, A. et al. (2003) Proc Natl Acad Sci u S A. 100 : 5170-5174.; ; Abrami L. et al. (2003) J. Cell Biol. 160 : 321-328;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 1mM DTT, 0.1M NaCl

Neuroscience

NP_001139266

P58335

Human

QEQPSCR RAFDLYFVLD KSGSVANNWI EIYNFVQQLA ERFVSPEMRL SFIVFSSQAT IILPLTGDRG KISKGLEDLK RVSPVGETYI HEGLKLANEQ IQKAGGLKTS SIIIALTDGK LDGLVPSYAE KEAKISRSLG ASVYCVGVLD FEQAQLERIA DSKEQVFPVK GGFQALKGII NSILAQSCTE ILELQPSSVC VGEEFQIVLS GRGFMLGSRN GSVLCTYTVN ETYTTSVKPV SVQLNSMLCP APILNKAGET LDVSVSFNGG KSVISGSLIV TATECSN