Recombinant humaan CPEB1-eiwit

CPEB1 is a member of the cytoplasmic polyadenylation element (CPE) binding protein family. This highly conserved protein binds to a specific RNA sequence called the CPE found in the 3' uTR of some mRNAs. Similar proteins in Xenopus and mouse function to induce cytoplasmic polyadenylation of dormant mRNAs with short polyA tails, resulting in their translation. Members of this protein family regulate translation of cyclin B1 during embryonic cell divisions. Recombinant human CPEB1 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Cytoplasmic polyadenylation element bindi ng protein 1, CEBP, CPE-BP1, CPEB

E.coli

Human

His-Tag

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

64.5 kDa (584aa)

CPEB1, Cytoplasmic polyadenylation element bindi ng protein 1, CEBP, CPE-BP1, CPEB, ATGP2659-10 µg, ATGP2659-20 µg, ATGP2659-50 µg, ATGP2659-100 µg, ATGP2659-250 µg, ATGP2659-500 µg, ATGP2659-1 mg, ATGP2659-10, ATGP2659-20, ATGP2659-50, ATGP2659-100, ATGP2659-250, ATGP2659-500, ATGP2659-1

Sasayama T., et al. (2005) Genes Cells. 10:627-638; ; Wilczynska A., et al. (2005) J. Cell Sci. 118:981-992;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Epigenomics (Transcription & Translation)

NP_085097

Q9BZB8

Human

MGSSHHHHHH SSGLVPRGSH MGSMAFPLEE EAGRIKDCWD NQEAPALSTC SNANIFRRIN AILDNSLDFS RVCTTPINRG IHDHLPDFQD SEETVTSRML FPTSAQESSR GLPDANDLCL GLQSLSLTGW DRPWSTQDSD SSAQSSTHSV LSMLHNPLGN VLGKPPLSFL PLDPLGSDLV DKFPAPSVRG SRLDTRPILD SRSSSPSDSD TSGFSSGSDH LSDLISSLRI SPPLPFLSLS GGGPRDPLKM GVGSRMDQEQ AALAAVTPSP TSASKRWPGA SVWPSWDLLE APKDPFSIER EARLHRQAAA VNEATCTWSG QLPPRNYKNP IYSCKVFLGG VPWDITEAGL VNTFRVFGSL SVEWPGKDGK HPRCPPKGYV YLVFELEKSV RSLLQACSHD PLSPDGLSEY YFKMSSRRMR CKEVQVIPWV LADSNFVRSP SQRLDPSRTV FVGALHGMLN AEALAAILND LFGGVVYAGI DTDKHKYPIG SGRVTFNNQR SYLKAVSAAF VEIKTTKFTK KVQIDPYLED SLCHICSSQP GPFFCRDQVC FKYFCRSCWH WRHSMEGLRH HSPLMRNQKN RDSS