Recombinant humaan CRACC/SLAMF7 eiwit

SLAMF7, also known as SLAM family member 7, is a single-pass type 1 membrane protein and a member of the CS2 family of cell surface receptors. Isoform 1 of this protein mediates NK cell activation through a SH2D1A-independent extracellular signal-regulated ERK-mediated pathway. It may play a role in lymphocyte adhesion. SLAMF7 can exert activating of inhibitory influences on cells of the immune system depending on cellular context and the availability of effector proteins. Recombinant human SLAMF7, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

SLAMF7, CD2 subset 1, CD2-like receptor-activating cytotoxic cells, CRACC, CS1, CD319, Membrane protein FOAP-12, Novel Ly9, Protein 19A

Baculovirus

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 95% by SDS-PAGE

23.4 kDa (212aa)

CRACSLAMF7, SLAMF7, CD2 subset 1, CD2-like receptor-activating cytotoxic cells, CRACC, CS1, CD319, ATGP3258-10 µg, ATGP3258-20 µg, ATGP3258-50 µg, ATGP3258-100 µg, ATGP3258-250 µg, ATGP3258-500 µg, ATGP3258-1 mg, ATGP3258-10, ATGP3258-20, ATGP3258-50, ATGP3258-100, ATGP3258-250, ATGP3258-500, ATGP3258-1

Kim JR et al., (2013) Inflamm. Res. 62 (8) :765-772.; ; Kramer B et al., (2013) Infect. Immun. 81 (3) :690-696.

Kikuchi J, et al. Soluble SLAMF7 promotes the growth of myeloma cells via homophilic interaction with surface SLAMF7. (Leukemia. 2020) {https://pubmed.ncbi.nlm.nih.gov/31358854/}

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Immunology

NP_067004

Q9NQ25

Human