Recombinant humaan Crystalline mu/CRYM eiwit

Crystallin mu, also known as CRYM, is a member of the crystallin protein family. Crystallins are separated into two classes, taxon-specific and ubiquitous. This gene encodes a taxon-specific crystallin protein. The human CRYM gene maps to chromosome 16p13. 11, and encodes a protein that is expressed in neural tissue, muscle, and kidney. unlike other crystallins, CRYM does not perform a structural role in lens tissue, but rather it binds NADPH and thyroid hormone, which indicates that it may have other regulatory or developmental functions. Recombinant human CRYM, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Crystallin mu, Ketimine reductase mu-crystallin, NADP-regulated thyroid-hormone-binding protein, Thiomorpholine-carboxylate dehydrogenase, mu-crystallin, DFNA40, THBP

E.coli

Human

His-Tag

SDS-PAGE

1 mg/mL (determined by Bradford assay)

> 95% by SDS-PAGE

35.9 kDa (334aa) confirmed by MALDI-TOF

CRYM, Crystallin mu, THBP, Crystallin mu CRYM, DFNA 40, DFNA40, Mu crystallin homolog, NADP regulated thyroid hormone binding protein, OTTHuMP00000115878., ATGP0559-10 µg, ATGP0559-20 µg, ATGP0559-50 µg, ATGP0559-100 µg, ATGP0559-250 µg, ATGP0559-500 µg, ATGP0559-1 mg, ATGP0559-10, ATGP0559-20, ATGP0559-50, ATGP0559-100, ATGP0559-250, ATGP0559-500, ATGP0559-1

Kim RY., et al. (1992) . Proc Natl Acad Sci uSA. 89 (19) :9292-6.; ; Muaders NW., et al. (1988) J Biol Chem. 263:15462-15466.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol

Neuroscience

NP_001879

Q14894

Human

MGSSHHHHHH SSGLVPRGSH> MSRVPAFLSA AEVEEHLRSS SLLIPPLETA LANFSSGPEG <GVMQPVRTVV PVTKHRGYLG VMPAYSAAED ALTTKLVTFY EDRGITSVVP SHQATVLLFE PSNGTLLAVM DGNVITAKRT AAVSAIATKF LKPPSSEVLC ILGAGVQAYS HYEIFTEQFS FKEVRIWNRT KENAEKFADT VQGEVRVCSS VQEAVAGADV IITVTLATEP ILFGEWVKPG AHINAVGASR PDWRELDDEL MKEAVLYVDS QEAALKESGD VLLSGAEIFA ELGEVIKGVK PAHCEKTTVF KSLGMAVEDT VAAKLIYDSW SSGK