Recombinant humaan CST11-eiwit

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. CST11 is located in the cystatin locus and encodes an epididymal-specific protein whose specific function has not been determined. Recombinant human CST11 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Cystatin 11, CST8L, CTES2, dJ322G13.6, SC13

E.coli

Human

His-Tag

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

11.8 kDa (101aa)

CST11, Cystatin 11, CST8L, CTES2, dJ322G13.6, SC13, ATGP2117-10 µg, ATGP2117-20 µg, ATGP2117-50 µg, ATGP2117-100 µg, ATGP2117-250 µg, ATGP2117-500 µg, ATGP2117-1 mg, ATGP2117-10, ATGP2117-20, ATGP2117-50, ATGP2117-100, ATGP2117-250, ATGP2117-500, ATGP2117-1

Hamil K.G., et al. (2002) Endocrinology. 143:2787-2796; ; Deloukas P., et al. (2001) Nature. 414:865-871

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Protease inhibitors

NP_543020

Q9H112

Human

MGSSHHHHHH SSGLVPRGSH MGSARKKTFL SVHEVMAVEN YAKDSLQWIT DQYNKESDDK YHFRIFRVLK VQRQQVNCFF SVFAVPWFEQ YKILNKSCSS D