Recombinant humaan CXADR-eiwit

CXADR is a type I membrane receptor for group B coxsackieviruses and subgroup C adenoviruses. Several transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene are found on chromosomes 15, 18, and 21. Recombinant human CXADR protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Coxsackievirus and adenovirus receptor isoform 1, CAR; CAR4/6; HCAR

E.coli

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

26 kDa (241aa) confirmed by MALDI-TOF

CXADR, Coxsackievirus and adenovirus receptor isoform 1, CAR; CAR4/6; HCAR, ATGP2201-10 µg, ATGP2201-20 µg, ATGP2201-50 µg, ATGP2201-100 µg, ATGP2201-250 µg, ATGP2201-500 µg, ATGP2201-1 mg, ATGP2201-10, ATGP2201-20, ATGP2201-50, ATGP2201-100, ATGP2201-250, ATGP2201-500, ATGP2201-1

Burckhardt CJ, Suomalainen M, et al. (2011) . Cell Host Microbe. 10 (2) :105-17.; ; Hussain F, Morton PE, et al. (2011) . PLoS One. 6 (8) :e23056. ;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT

Signal Transduction

NP_001329

P78310

Human

MGSSHHHHHH SSGLVPRGSH MGSLSITTPE EMIEKAKGET AYLPCKFTLS PEDQGPLDIE WLISPADNQK VDQVIILYSG DKIYDDYYPD LKGRVHFTSN DLKSGDASIN VTNLQLSDIG TYQCKVKKAP GVANKKIHLV VLVKPSGARC YVDGSEEIGS DFKIKCEPKE GSLPLQYEWQ KLSDSQKMPT SWLAEMTSSV ISVKNASSEY SGTYSCTVRN RVGSDQCLLR LNVVPPSNKA G