Recombinant humaan CXC-R3-eiwit met C-terminaal humaan Fc-tag
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Expression Host : HEK293 The protein has a predicted molecular mass of 31.35 kDa after removal of the signal peptide. This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant) . Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716) .
C-X-C chemokine receptor type 3, CXC-R3, CXCR-3, CKR-L2?G protein-coupled receptor 9?CD183?IP-10 receptor
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Delivery in 4-6 weeks
Store at -80°C for 12 months (Avoid repeated freezing and thawing)
Beschrijving
Expression Host : HEK293 The protein has a predicted molecular mass of 31.35 kDa after removal of the signal peptide. This gene encodes a G protein-coupled rece
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