Recombinant humaan Cystatine-9 eiwit

Cystatin 9, also known as CST9, is a member of the CRES (cystatin-related epididymal spermatogenic) subfamily. The CRES (cystatin-related epididymal spermatogenic) protein defines a newsubgroup in the family 2 cystatins of the cystatin superfamily. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. CST9 is expressed in heart, placenta, lung, liver, skeletal muscle and pancreas. CST9 is thought to play a role in hematopoietic differentiation or inflammation. It has also been shown to be upregulated by LPS in some cancer cell lines, such as promyelocytic leukemia (HL-60) and myelomonocytic leukemia. Recombinant human CST9 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Cystatin 9, CLM

E.coli

Human

His-Tag

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

17.2 kDa (152aa)

Cystatin9, Cystatin 9, CLM, ATGP1256-10 µg, ATGP1256-20 µg, ATGP1256-50 µg, ATGP1256-100 µg, ATGP1256-250 µg, ATGP1256-500 µg, ATGP1256-1 mg, ATGP1256-10, ATGP1256-20, ATGP1256-50, ATGP1256-100, ATGP1256-250, ATGP1256-500, ATGP1256-1

Sun H., et al. (2003) Biochem Biophys Res Commun. 301:176-182.; ; Von Horsten H H., et al. (2007) J Biol Chem. 282:32912-32923.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Protease inhibitors

NP_001008693

Q5W186

Human

WCSEEEMGG NNKIVQDPMF LATVEFALNT FNVQSKEEHA YRLLRVLSSW REDSMDRKWR GKMVFSMNLQ LRQTVCRKFE DDIDNCPFQE SLELNNVRQG ISFPQVHSCG CCMGCGVGTG AADKAIPRDK GK