Recombinant humaan cytokeratine 19 eiwit

KRT19 is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. Recombinant human KRT19 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Keratin type I cytoskeletal 19, Keratin, type I cytoskeletal 19, CK19, K19, K1CS

E.coli

Human

His-Tag

SDS-PAGE, Denatured

0.5 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

46.5 kDa (423aa)

Cytokeratin19, Keratin type I cytoskeletal 19, Keratin, type I cytoskeletal 19, CK19, K19, K1CS, ATGP1939-10 µg, ATGP1939-20 µg, ATGP1939-50 µg, ATGP1939-100 µg, ATGP1939-250 µg, ATGP1939-500 µg, ATGP1939-1 mg, ATGP1939-10, ATGP1939-20, ATGP1939-50, ATGP1939-100, ATGP1939-250, ATGP1939-500, ATGP1939-1

Vilardell, F., et al. (2012) Virchows Arch. 460 (6), 569-575; ; Leelawat, K., et al. (2012) World J. Gastroenterol. 18 (2), 175-181

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M uREA, 10% glycerol

Cytoskeleton

NP_002267

P08727

Human

MGSSHHHHHH SSGLVPRGSH MGSMTSYSYR QSSATSSFGG LGGGSVRFGP GVAFRAPSIH GGSGGRGVSV SSARFVSSSS SGAYGGGYGG VLTASDGLLA GNEKLTMQNL NDRLASYLDK VRALEAANGE LEVKIRDWYQ KQGPGPSRDY SHYYTTIQDL RDKILGATIE NSRIVLQIDN ARLAADDFRT KFETEQALRM SVEADINGLR RVLDELTLAR TDLEMQIEGL KEELAYLKKN HEEEISTLRG QVGGQVSVEV DSAPGTDLAK ILSDMRSQYE VMAEQNRKDA EAWFTSRTEE LNREVAGHTE QLQMSRSEVT DLRRTLQGLE IELQSQLSMK AALEDTLAET EARFGAQLAH IQALISGIEA QLGDVRADSE RQNQEYQRLM DIKSRLEQEI ATYRSLLEGQ EDHYNNLSAS KVL