Recombinant humaan DcR3/TNFRSF6B eiwit

TNFRSF6B belongs to Tumor necrosis factor receptor superfamily. It acts as a decoy receptor that competes with death receptors for ligand binding. This protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death and T cell activation as well as to induce angiogenesis via neutralization of TL1A. Recombinant human TNFRSF6B protein, fused to His-tag at N-terminus, was expressed in E. coli.

Tumor necrosis factor receptor superfamily member 6B, M68, TR6, DCR3, Decoy receptor 3, Decoy receptor for Fas ligand, DJ583P15.1.1

E.coli

Human

His-Tag

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

32.1 kDa (294aa)

DcR3, TNFRSF6B, Tumor necrosis factor receptor superfamily member 6B, Tumor necrosis factor receptor superfamily member 6B, DCR3, DJ583P15.1.1, Decoy receptor 3, Decoy receptor for Fas ligand, M68, TR6, ATGP2416-10 µg, ATGP2416-20 µg, ATGP2416-50 µg, ATGP2416-100 µg, ATGP2416-250 µg, ATGP2416-500 µg, ATGP2416-1 mg, ATGP2416-10, ATGP2416-20, ATGP2416-50, ATGP2416-100, ATGP2416-250, ATGP2416-500, ATGP2416-1

Pitti RM. et al. (1999) Nature. 396 : 699-703..; ; Yu KY. et al. (1999) J Biol Chem. 274: 13733-13736;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.4M urea

Immunology

NP_003814.1

O95407

Human

VAETPTY PWRDAETGER LVCAQCPPGT FVQRPCRRDS PTTCGPCPPR HYTQFWNYLE RCRYCNVLCG EREEEARACH ATHNRACRCR TGFFAHAGFC LEHASCPPGA GVIAPGTPSQ NTQCQPCPPG TFSASSSSSE QCQPHRNCTA LGLALNVPGS SSHDTLCTSC TGFPLSTRVP GAEECERAVI DFVAFQDISI KRLQRLLQAL EAPEGWGPTP RAGRAALQLK LRRRLTELLG AQDGALLVRL LQALRVARMP GLERSVRERF LPVH