Recombinant humaan DCUN1D1-eiwit

DCuN1D1, also known as DCN1-like protein 1, is involved in the malignant transformation of squamous cell lineage. This protein regulates Gli1, a key regulator of the hedgehog (HH) pathway that plays an important role in development, maintenance, and regeneration of almost all adult tissues. Recombinant human DCuN1D1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

DCN1-like protein 1, DCuN1L1, RP42, SCCRO, SCRO, Tes3

E.coli

Human

His-Tag

SDS-PAGE

1 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

32.2 kDa (279aa) confirmed by MALDI-TOF

DCUN1D1, DCN1-like protein 1, DCuN1L1, RP42, SCCRO, SCRO, Tes3, ATGP0884-10 µg, ATGP0884-20 µg, ATGP0884-50 µg, ATGP0884-100 µg, ATGP0884-250 µg, ATGP0884-500 µg, ATGP0884-1 mg, ATGP0884-10, ATGP0884-20, ATGP0884-50, ATGP0884-100, ATGP0884-250, ATGP0884-500, ATGP0884-1

Estilo C.L., et al. (2003) . Clin. Cancer Res, 9: 2300-2306.; ; Lum L., et al. (2004) . Science., 304: 1755-1759.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.1M NaCl

Cancer

NP_065691

Q96GG9

Human

MNKLKSSQKD KVRQFMIFTQ SSEKTAVSCL SQNDWKLDVA TDNFFQNPEL YIRESVKGSL DRKKLEQLYN RYKDPQDENK IGIDGIQQFC DDLALDPASI SVLIIAWKFR AATQCEFSKQ EFMDGMTELG CDSIEKLKAQ IPKMEQELKE PGRFKDFYQF TFNFAKNPGQ KGLDLEMAIA YWNLVLNGRF KFLDLWNKFL LEHHKRSIPK DTWNLLLDFS TMIADDMSNY DEEGAWPVLI DDFVEFARPQ IAGTKSTTV