Recombinant humaan DDR2-eiwit

DDR2, also known as discoidin domain-containing receptor 2, belongs to the discoidin-like domain containing subfamily of receptor tyrosine kinases. It is mainly expressed in mesenchymal cells and is unique amog RTKs in that its ligand is fibrillar collagen rather than a growth factor-like peptide. Recombinant human DDR2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Discoidin domain-containing receptor 2, DDR2, MIG20a, NTRKR3, TKT, TYR010, CD167 antigen-like family member B, CD167b, CD167b antigen, Cell migration inducing protein 20, DDR 2, DDR2_HUMAN, Discoidin domain containing receptor 2, Discoidin domain receptor 2, Discoidin domain receptor family member 2, discoidin domain receptor tyrosine kinase 2, Discoidin domain-containing receptor 2, discoidin domain-containing receptor tyrosine kinase 2, Hydroxyaryl protein kinase MIG20a, Migration inducing gene 16 protein Neurotrophic tyrosine kinase, Neurotrophic tyrosine kinase receptor related 3, NTRKR 3, NTRKR3, Receptor protein tyrosine kinase TKT, Receptor protein-tyrosine kinase TKT, Receptor related 3 receptor-related 3, TKT, TYRO 10, TYRO10, Tyrosine kinase receptor related to neurotrophic TRK, Tyrosine protein kinase TYRO 10, Tyrosine protein kinase TYRO10, Tyrosine-protein kinase TYRO10, Tyrosylprotein kinase

Baculovirus

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 90% by SDS-PAGE

43.7 kDa (386aa)

DDR2, Discoidin domain-containing receptor 2, DDR2, MIG20a, NTRKR3, TKT, TYR010, CD167 antigen-like family member B, CD167b, CD167b antigen, Cell migration inducing protein 20, DDR 2, DDR2_HUMAN, Discoidin domain containing receptor 2, Discoidin domain receptor 2, Discoidin domain receptor family member 2, discoidin domain receptor tyrosine kinase 2, Discoidin domain-containing receptor 2, discoidin domain-containing receptor tyrosine kinase 2, Hydroxyaryl protein kinaseMIG20a, Migration inducing gene 16 proteinNeurotrophic tyrosine kinase, Neurotrophic tyrosine kinase receptor related 3, NTRKR 3, NTRKR3, Receptor protein tyrosine kinase TKT, Receptor protein-tyrosine kinase TKT, Receptor related 3receptor-related 3, TKT, TYRO 10, TYRO10, Tyrosine kinase receptor related to neurotrophic TRK, Tyrosine protein kinase TYRO 10, Tyrosine protein kinase TYRO10, Tyrosine-protein kinase TYRO10, Tyrosylprotein kinase, ATGP3380-10 µg, ATGP3380-20 µg, ATGP3380-50 µg, ATGP3380-100 µg, ATGP3380-250 µg, ATGP338

Vogel WF., et al. (2006) Cell. Signal. 18:1108-1116.; ; Wall SJ., et al. (2005) J Biol Chem. 48:40187-40194.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Neuroscience

NP_001014796.1

Q16832

Human

Lys22