Recombinant humaan decorine-eiwit

DCN, also known as decorin isoform, is a small secreted chondroitin/dermatan sulfate proteoglycan within the family of small leucine-rich proteoglycans (SLRPs) . This protein has been implicated in matrix assembly and may suppress the growth of various tumor cell lines by inhibiting the epidermal growth factor receptor. Recombinant human DCN, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques

DCN, DSPG2, SLRR1B, decorin proteoglycan, Bone proteoglycan II, PG-S2, PG40, CSCD, PGII, PGS2

Baculovirus

Human

His-Tag

SDS-PAGE

1 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 95% by SDS-PAGE

37.7 kDa (340aa)

Decorin, Decorin isoform, CSCD, DSPG2, PG40, PGII, PGS2, SLRR1B, ATGP3174-10 µg, ATGP3174-20 µg, ATGP3174-50 µg, ATGP3174-100 µg, ATGP3174-250 µg, ATGP3174-500 µg, ATGP3174-1 mg, ATGP3174-10, ATGP3174-20, ATGP3174-50, ATGP3174-100, ATGP3174-250, ATGP3174-500, ATGP3174-1

Mogyorsi A., et al. (1999) Nephrol Dial Transplant. 14 (5) :1078-1081.; ; Reed CC., et al. (2002) Glycoconj J. 19 (4-5) :249-255.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Signal Transduction

NP_001911

P07585

Human

DEASG IGPEVPDDRD FEPSLGPVCP FRCQCHLRVV QCSDLGLDKV PKDLPPDTTL LDLQNNKITE IKDGDFKNLK NLHALILVNN KISKVSPGAF TPLVKLERLY LSKNQLKELP EKMPKTLQEL RAHENEITKV RKVTFNGLNQ MIVIELGTNP LKSSGIENGA FQGMKKLSYI RIADTNITSI PQGLPPSLTE LHLDGNKISR VDAASLKGLN NLAKLGLSFN SISAVDNGSL ANTPHLRELH LDNNKLTRVP GGLAEHKYIQ VVYLHNNNIS VVGSSDFCPP GHNTKKASYS GVSLFSNPVQ YWEIQPSTFR CVYVRSAIQL GNYK