Recombinant humaan DEFB118 eiwit

DEFB118 is a member of the beta subfamily of defensins. Beta-defensins are antimicrobial peptides that protect tissues and organs from infection by a variety of microorganisms. Expression of this gene is regulated by androgen, and the encoded protein binds to sperm and exhibits antibacterial activity. This protein is found in a cluster with other beta-defensin genes on the long arm of chromosome 20. Recombinant human DEFB118 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Beta-defensin 118 precursor, C20orf63; DEFB-18; ESC42, ESP13.6

E.coli

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

13.8 kDa (126aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

DEFB118, Beta-defensin 118 precursor, C20orf63; DEFB-18; ESC42, ESP13.6, ATGP2453-10 µg, ATGP2453-20 µg, ATGP2453-50 µg, ATGP2453-100 µg, ATGP2453-250 µg, ATGP2453-500 µg, ATGP2453-1 mg, ATGP2453-10, ATGP2453-20, ATGP2453-50, ATGP2453-100, ATGP2453-250, ATGP2453-500, ATGP2453-1

Kao CY, Chen Y, et al. (2003) . Am J Respir Cell Mol Biol. 29 (1) :71-80.; ; Schutte BC, Mitros JP, et al. (2002) . Proc Natl Acad Sci u S A. 99 (4) :2129-33.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol, 1mM DTT

Immunology

NP_473453

Q96PH6

Human

MGSSHHHHHH SSGLVPRGSH MGSYSGEKKC WNRSGHCRKQ CKDGEAVKDT CKNLRACCIP SNEDHRRVPA TSPTPLSDST PGIIDDILTV RFTTDYFEVS SKKDMVEESE AGRGTETSLP NVHHSS