Recombinant humaan DLX3-eiwit

Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. Trichodentoosseous syndrome (TDO), an autosomal dominant condition, has been correlated with DLX3 gene mutation. This gene is located in a tail-to-tail configuration with another member of the gene family on the long arm of chromosome 17. Mutations in DLX3 have been associated with the autosomal dominant conditions trichodentoosseous syndrome and amelogenesis imperfecta with taurodontism. Recombinant human DLX3 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Homeobox protein DLX-3, AI4, TDO

E.coli

Human

His-Tag

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

23.4 kDa (209aa)

DLX3, homeobox protein DLX-3, AI4, TDO, ATGP2482-10 µg, ATGP2482-20 µg, ATGP2482-50 µg, ATGP2482-100 µg, ATGP2482-250 µg, ATGP2482-500 µg, ATGP2482-1 mg, ATGP2482-10, ATGP2482-20, ATGP2482-50, ATGP2482-100, ATGP2482-250, ATGP2482-500, ATGP2482-1

Price J.A., et al (1998) . Hum. Mol. Genet. 7:563-569

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Epigenomics (Transcription & Translation)

NP_005211.1

O60479

Human

MSGSFDR KLSSILTDIS SSLSCHAGSK DSPTLPESSV TDLGYYSAPQ HDYYSGQPYG QTVNPYTYHH QFNLNGLAGT GAYSPKSEYT YGASYRQYGA YREQPLPAQD PVSVKEEPEA EVRMVNGKPK KVRKPRTIYS SYQLAALQRR FQKAQYLALP ERAELAAQLG LTQTQVKIWF QNRRSKFKK