Recombinant humaan DNAL1-eiwit

DNAL1 is an axonemal dynein light chain which functions as a component of the outer dynein arms complex. This complex acts as the molecular motor that provides the force to move cilia in an ATP-dependent manner. DNAL1 is expressed in tissues with motile cilia or flagella and may be involved in the movement of sperm flagella. Alternate splicing results in multiple transcript variants. Recombinant human DNAL1 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Dynein light chain 1 axonemal, Dynein light chain 1, axonemal, C14orf168, CILD16

E.coli

Human

His-Tag

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

23.9 kDa (213aa)

DNAL1, Dynein light chain 1 axonemal, Dynein light chain 1, axonemal, C14orf168, CILD16, ATGP1958-10 µg, ATGP1958-20 µg, ATGP1958-50 µg, ATGP1958-100 µg, ATGP1958-250 µg, ATGP1958-500 µg, ATGP1958-1 mg, ATGP1958-10, ATGP1958-20, ATGP1958-50, ATGP1958-100, ATGP1958-250, ATGP1958-500, ATGP1958-1

Horvath J, Fliegauf M, et al. (2005) . Am J Respir Cell Mol Biol. 33 (1) :41-7.; ; Lancaster MA, et al. (2009) . Curr Opin Genet Dev. 19 (3) :220-9.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Cytoskeleton

NP_113615

Q4LDG9

Human

MGSSHHHHHH SSGLVPRGSH MGSMAKATTI KEALARWEEK TGQRPSEAKE IKLYAQIPPI EKMDASLSML ANCEKLSLST NCIEKIANLN GLKNLRILSL GRNNIKNLNG LEAVGDTLEE LWISYNFIEK LKGIHIMKKL KILYMSNNLV KDWAEFVKLA ELPCLEDLVF VGNPLEEKHS AENNWIEEAT KRVPKLKKLD GTPVIKGDEE EDN