Recombinant humaan DYNLT1-eiwit

Dynein light chain Tctex-type 1, also known as DYNLT1, belongs to the dynein light chain Tctex-type family. DYNLT1 acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein is the major motor protein complex responsible for minus-end, microtubule-based motile processes. Each dynein complex consists of 2 heavy chains that have ATPase and motor activities, plus a group of accessory polypeptides. DYNLT1 is a dynein light chain involved in cargo binding. Recombinant human DYNLT1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Dynein light chain Tctex-type 1, CW-1, TCTEL1, tctex-1

E.coli

Human

His-Tag

SDS-PAGE

1 mg/mL (determined by Bradford assay)

> 95% by SDS-PAGE

14.6 kDa (133aa) confirmed by MALDI-TOF

DYNLT1, Dynein light chain Tctex-type 1, CW-1, TCTEL1, tctex-1, ATGP1035-10 µg, ATGP1035-20 µg, ATGP1035-50 µg, ATGP1035-100 µg, ATGP1035-250 µg, ATGP1035-500 µg, ATGP1035-1 mg, ATGP1035-10, ATGP1035-20, ATGP1035-50, ATGP1035-100, ATGP1035-250, ATGP1035-500, ATGP1035-1

Asai D J., et al. (2004) J Eukaryot Microbiol. 51:23-29.; ; He Y., et al. (2005) J Cell Biol. 168:697-703.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 30% glycerol, 0.1M NaCl

Cytoskeleton

NP_006510

P63172

Human

MEDYQAAEET AFVVDEVSNI VKEAIESAIG GNAYQHSKVN QWTTNVVEQT LSQLTKLGKP FKYIVTCVIM QKNGAGLHTA SSCFWDSSTD GSCTVRWENK TMYCIVSAFG LSI