Recombinant humaan EMAP-II-eiwit

AIMP1, also known as EMPA2 or p43, is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells. Recombinant human AIMP1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Aminoacyl tRNA synthase complex-interacting multifunctional protein 1, Aminoacyl tRNA synthase complex-interacting multifunctional protein 1, EMAP2, EMAPII, p43, SCYE1

E.coli

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by BCA assay)

> 85% by SDS-PAGE

39.2 kDa (356aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

EMAP-2, Aminoacyl tRNA synthase complex-interacting multifunctional protein 1, Aminoacyl tRNA synthase complex-interacting multifunctional protein 1, EMAP2, EMAPII, p43, SCYE1, ATGP0852-10 µg, ATGP0852-20 µg, ATGP0852-50 µg, ATGP0852-100 µg, ATGP0852-250 µg, ATGP0852-500 µg, ATGP0852-1 mg, ATGP0852-10, ATGP0852-20, ATGP0852-50, ATGP0852-100, ATGP0852-250, ATGP0852-500, ATGP0852-1

Zhu X., et al. (2009) Proc Natl Acad Sci u S A. 106 (37) :15944-9.; ; Kim E., et al. (2008) J Immunol. 180 (5) :2894-902.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 2mM DTT, 10% glycerol

Cancer

NP_001135888

Q12904

Human

MGSSHHHHHH SSGLVPRGSH MLPAVAVSEP VVLRFMIFCR LLAKMANNDA VLKRLEQKGA EADQIIEYLK QQVSLLKEKA ILQATLREEK KLRVENAKLK KEIEELKQEL IQAEIQNGVK QIPFPSGTPL HANSMVSENV IQSTAVTTVS SGTKEQIKGG TGDEKKAKEK IEKKGEKKEK KQQSIAGSAD SKPIDVSRLD LRIGCIITAR KHPDADSLYV EEVDVGEIAP RTVVSGLVNH VPLEQMQNRM VILLCNLKPA KMRGVLSQAM VMCASSPEKI EILAPPNGSV PGDRITFDAF PGEPDKELNP KKKIWEQIQP DLHTNDECVA TYKGVPFEVK GKGVCRAQTM SNSGIK