Recombinant humaan EpCAM/TROP-1-eiwit

Epithelial cell adhesion molecules, also known as EPCAM, may act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. This protein plays a role in embryonic stem cells proliferation and differentiation. Recombinant human EPCAM protein, fused to His-tag at N-terminus, was expressed in E. coli.

Epithelial cell adhesion molecules, CD326, KS1/4, KSA, M4S1, MIC18, MK-1, TACSTD1, TROP1, DIAR5, EGP, GA733 2, HNPCC8

E.coli

Human

His-Tag

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

30.1 kDa (267aa)

EpCAM, TROP1, Epithelial cell adhesion molecules, CD326, KS1/4, KSA, M4S1, MIC18, MK-1, TACSTD1, TROP1, DIAR5, EGP, GA733 2, HNPCC8, ATGP1845-10 µg, ATGP1845-20 µg, ATGP1845-50 µg, ATGP1845-100 µg, ATGP1845-250 µg, ATGP1845-500 µg, ATGP1845-1 mg, ATGP1845-10, ATGP1845-20, ATGP1845-50, ATGP1845-100, ATGP1845-250, ATGP1845-500, ATGP1845-1

Muenz M., et al. (2004) Oncogene.23:5748-5758; ; Muenz M., et al. (2005) Cancer Lett. 225:151-157;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Cancer

NP_002345

P16422

Human

QEECV CENYKLAVNC FVNNNRQCQC TSVGAQNTVI CSKLAAKCLV MKAEMNGSKL GRRAKPEGAL QNNDGLYDPD CDESGLFKAK QCNGTSMCWC VNTAGVRRTD KDTEITCSER VRTYWIIIEL KHKAREKPYD SKSLRTALQK EITTRYQLDP KFITSILYEN NVITIDLVQN SSQKTQNDVD IADVAYYFEK DVKGESLFHS KKMDLTVNGE QLDLDPGQTL IYYVDEKAPE FSMQGLK