Recombinant humaan EpCAM/TROP-1-eiwit

TACSTD1, also known as tumor-associated calcium signal transducer 1, is a membrane glycoprotein expressed on adenomatous and simple epithelia, where it is involved in homophilic adhesion at the basolateral membrane. It may act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. It plays a role in embryonic stem cells proliferation and differentiation. Recombinant human TACSTD1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

TACSTD1, CD326, CO17-1A, EGP, EGP40, Ep-CAM, GA733-2, hEGP-2, KSA, M4S1, MIC18, MK-1, TROP1

Baculovirus

Human

His-Tag

SDS-PAGE

1 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 95% by SDS-PAGE

28.2 kDa (248aa)

EpCAM, TROP1, TACSTD1, CD326, CO17-1A, EGP, EGP40, Ep-CAM, GA733-2, hEGP-2, KSA, M4S1, MIC18, MK-1, TROP1, ATGP3189-10 µg, ATGP3189-20 µg, ATGP3189-50 µg, ATGP3189-100 µg, ATGP3189-250 µg, ATGP3189-500 µg, ATGP3189-1 mg, ATGP3189-10, ATGP3189-20, ATGP3189-50, ATGP3189-100, ATGP3189-250, ATGP3189-500, ATGP3189-1

Muenz M., et al. (2003) Oncogene. 23:5748-5758.; ; Lu TY., et al. (2009) J Biol Chem. 285:8719-8732

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Cancer

NP_002345.1

P16422

Human