Recombinant humaan EPCR-eiwit

PROCR is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. This protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy. The encoded protein may also play a role in malarial infection and has been associated with cancer. Recombinant human PROCR protein, fused to His-tag at N-terminus, was expressed in E. coli.

Protein C receptor endothelial, Protein C receptor, endothelial, CCCA, CCD41, CD201, EPCR

E.coli

Human

His-Tag

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 80% by SDS-PAGE

24.4 kDa (216aa)

EPCR, Protein C receptor endothelial, Protein C receptor, endothelial, CCCA, CCD41, CD201, EPCR, ATGP2638-10 µg, ATGP2638-20 µg, ATGP2638-50 µg, ATGP2638-100 µg, ATGP2638-250 µg, ATGP2638-500 µg, ATGP2638-1 mg, ATGP2638-10, ATGP2638-20, ATGP2638-50, ATGP2638-100, ATGP2638-250, ATGP2638-500, ATGP2638-1

Fukudome K. et al. (1994) J Biol Chem. 269:26486-26491.; ; Van de Wouwer M. et al. (2005) Arterioscler. Thromb. Vasc. Biol. 24:1374-83.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.4M urea

Cardiovascular

NP_006395

Q9UNN8

Human

MGSSHHHHHH SSGLVPRGSH MGSSQDASDG LQRLHMLQIS YFRDPYHVWY QGNASLGGHL THVLEGPDTN TTIIQLQPLQ EPESWARTQS GLQSYLLQFH GLVRLVHQER TLAFPLTIRC FLGCELPPEG SRAHVFFEVA VNGSSFVSFR PERALWQADT QVTSGVVTFT LQQLNAYNRT RYELREFLED TCVQYVQKHI SAENTKGSQT SRSYTS