Recombinant humaan EPCR-eiwit

PROCR, also known as endothelial protein C receptor, is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. It is a transmembrane glycoprotein expressed on vascular endothelial cells and functions as a negative regulator of thrombosis. Recombinant human PROCR protein, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Endothelial protein C receptor, PROCR, CCCA, CCD41, EPCR

Baculovirus

Human

HIgG-His-Tag

SDS-PAGE

0.5 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 95% by SDS-PAGE

49.3 kDa (435aa)

EPCR, Endothelial protein C receptor, PROCR, CCCA, CCD41, EPCR, ATGP3604-10 µg, ATGP3604-20 µg, ATGP3604-50 µg, ATGP3604-100 µg, ATGP3604-250 µg, ATGP3604-500 µg, ATGP3604-1 mg, ATGP3604-10, ATGP3604-20, ATGP3604-50, ATGP3604-100, ATGP3604-250, ATGP3604-500, ATGP3604-1

Ghosh S., et al, (2007) J Biol Chem. 282:11849-11857.; ; Keshava S., et al, (2013) J Thromb Haemost. 11 (11) :2062-2065.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Cardiovascular

NP_006395

Q9UNN8

Human

Ala

ADPSQDASDG LQRLHMLQIS YFRDPYHVWY QGNASLGGHL THVLEGPDTN TTIIQLQPLQ EPESWARTQS GLQSYLLQFH GLVRLVHQER TLAFPLTIRC FLGCELPPEG SRAHVFFEVA VNGSSFVSFR PERALWQADT QVTSGVVTFT LQQLNAYNRT RYELREFLED TCVQYVQKHI SAENTKGSQT SRSYTSLEPK SCDKTHTCPP CPAPELLGGP SVFLFPPKPK DTLMISRTPE VTCVVVDVSH EDPEVKFNWY VDGVEVHNAK TKPREEQYNS TYRVVSVLTV LHQDWLNGKE YKCKVSNKAL PAPIEKTISK AKGQPREPQV YTLPPSRDEL TKNQVSLTCL VKGFYPSDIA VEWESNGQPE NNYKTTPPVL DSDGSFFLYS KLTVDKSRWQ QGNVFSCSVM HEALHNHYTQ KSLSLSPGKH HHHHH