Recombinant humaan Epireguline-eiwit

EREG, also known as epiregulin, is a member of the epidermal growth factor family. It can function as a ligand of EGFR (epidermal growth factor receptor), as well as a ligand of most members of the ERBB (v-erb-b2 oncogene homolog) family of tyrosine-kinase receptors. It may be a mediator of localized cell proliferation. As a mitogen it may stimulate cell proliferation and/or angiogenesis. Recombinant human EREG protein, fused to His-tag at N-terminus, was expressed in E. coli.

Proepiregulin, Proepiregulin, ER

E.coli

Human

His-Tag

SDS-PAGE, Denatured

0.5 mg/mL (determined by Bradford assay)

> 80% by SDS-PAGE

7.7 kDa (69aa)

Epiregulin, Proepiregulin, Proepiregulin, ER, ATGP2923-10 µg, ATGP2923-20 µg, ATGP2923-50 µg, ATGP2923-100 µg, ATGP2923-250 µg, ATGP2923-500 µg, ATGP2923-1 mg, ATGP2923-10, ATGP2923-20, ATGP2923-50, ATGP2923-100, ATGP2923-250, ATGP2923-500, ATGP2923-1

Yun J. et al. (2012) Lab Invest. 92:1033-1044.; ; Thuong NT. et al. (2012) Genes Immun. 13:275-281.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Hormones & Cytokines

NP_001423

O14944

Human

MGSSHHHHHH SSGLVPRGSH MGSVSITKCS SDMNGYCLHG QCIYLVDMSQ NYCRCEVGYT GVRCEHFFL