Recombinant humaan ERLIN2-eiwit

ERLIN2, also known as SPFH2, is SPFH domain-containing proteins that belong to the prohibitin family. Also, this protein is a ubiquitously expressed 339 amino acid protein that belongs to the band 7/mec-2 family. Localized to lipid raft-like domains in the membrane of the endoplasmic reticulum (ER), ERLIN2 plays a crucial role in the ER-associated degradation (ERAD) pathway that removes metabolically regulated and aberrant proteins from the ER. Recombinant human ERLIN2 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Erlin-2, C8orf2, Erlin-2, NET32, SPFH2, SPG18

E.coli

Human

His-Tag

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 95% by SDS-PAGE

37.8 kDa (338aa)

ERLIN2, Erlin-2, C8orf2, Erlin-2, NET32, SPFH2, SPG18, ATGP1782-10 µg, ATGP1782-20 µg, ATGP1782-50 µg, ATGP1782-100 µg, ATGP1782-250 µg, ATGP1782-500 µg, ATGP1782-1 mg, ATGP1782-10, ATGP1782-20, ATGP1782-50, ATGP1782-100, ATGP1782-250, ATGP1782-500, ATGP1782-1

Browman D T., et al. (2006) J Cell Sci. 119:3149-60.; ; Ikeqawa S., et al. (1999) Cytogenet Cell Genet. 85:227-231.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 2M urea, 20% glycerol

Signal Transduction

NP_009106

O94905

Human

MGSSHHHHHH SSGLVPRGSH MGSKIEEGHI GVYYRGGALL TSTSGPGFHL MLPFITSYKS VQTTLQTDEV KNVPCGTSGG VMIYFDRIEV VNFLVPNAVY DIVKNYTADY DKALIFNKIH HELNQFCSVH TLQEVYIELF DQIDENLKLA LQQDLTSMAP GLVIQAVRVT KPNIPEAIRR NYELMESEKT KLLIAAQKQK VVEKEAETER KKALIEAEKV AQVAEITYGQ KVMEKETEKK ISEIEDAAFL AREKAKADAE CYTAMKIAEA NKLKLTPEYL QLMKYKAIAS NSKIYFGKDI PNMFMDSAGS VSKQFEGLAD KLSFGLEDEP LETATKEN