Recombinant humaan FAM3C-eiwit

FAB3C belongs to the FAM3 family and contains a GG domain. A change in expression of this protein has been noted in pancreatic cancer-derived cells. Fam3c may be a downstream target gene for the Nkx5. 1 transcription factor, and may thus be involved in cell differentiation and proliferation during inner ear embryogenesis. Also, it may be involved in retinal laminar formation and promotes epithelial to mesenchymal transition. Recombinant human FAM3C, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Protein FAM3C, ILEI, FAM3 metabolism regulating signaling molecule C, family with sequence similarity 3 member C, GS3876, predicted osteoblast protein, interleukin-like EMT inducer, interleukin-like epithelial-mesenchymal transition inducer

E.coli

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

24.5kD (224aa) confirmed by MALDI-TOF

FAM3C, Protein FAM3C, ILEI, ATGP1251-10 µg, ATGP1251-20 µg, ATGP1251-50 µg, ATGP1251-100 µg, ATGP1251-250 µg, ATGP1251-500 µg, ATGP1251-1 mg, ATGP1251-10, ATGP1251-20, ATGP1251-50, ATGP1251-100, ATGP1251-250, ATGP1251-500, ATGP1251-1

Zhu Y, et al. (2002) Genomics 80 (2) : 144-50.; ; Pilipenko VV, et al. (2004) Gene. 335:159-68.

Nakano M, et al. Extracellular Release of ILEI/FAM3C and Amyloid-β Is Associated with the Activation of Distinct Synapse Subpopulations. (J Alzheimers Dis. 2021) {https://pubmed.ncbi.nlm.nih.gov/33492290/}

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 5mM DTT, 20% glycerol, 200 mM NaCl

Immunology

NP_055703

Q92520

Human

MGSSHHHHHH SSGLVPRGSH MQVFEIKMDA SLGNLFARSA LDTAARSTKP PRYKCGISKA CPEKHFAFKM ASGAANVVGP KICLEDNVLM SGVKNNVGRG INVALANGKT GEVLDTKYFD MWGGDVAPFI EFLKAIQDGT IVLMGTYDDG ATKLNDEARR LIADLGSTSI TNLGFRDNWV FCGGKGIKTK SPFEQHIKNN KDTNKYEGWP EVVEMEGCIP QKQD