Recombinant humaan Fas Ligand/FASLG-eiwit

Fas ligand, also known as FASLG, belongs to the tumor necrosis factor family and is the ligand for FAS. Both are transmembrane proteins. Interaction of FAS with this ligand is critical in triggering apoptosis of some types of cells such as lymphocytes. Defects in FASLG may be related to some cases of systemic lupus erythematosus (SLE) . Recombinant human FASLG protein, fused to His-tag at N-terminus, was expressed in E. coli.

Fas antigen ligand (Fas ligand; FasL), Tumor necrosis factor ligand superfamily member 6 (TNFSF6), Apoptosis antigen ligand (APTL), CD95 ligand (CD95L), ADAM10-processed FasL form (APL), CD178, APT1LG1

E.coli

Human

His-Tag

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

19.6 kDa (173aa)

FASLG, Tumor necrosis factor ligand superfamily member 6, APT1LG1, CD178, CD95L, FASL, TNFSF6, ATGP1890-10 µg, ATGP1890-20 µg, ATGP1890-50 µg, ATGP1890-100 µg, ATGP1890-250 µg, ATGP1890-500 µg, ATGP1890-1 mg, ATGP1890-10, ATGP1890-20, ATGP1890-50, ATGP1890-100, ATGP1890-250, ATGP1890-500, ATGP1890-1

Kirkin V., et al. (2007) Cell Death Differ. 14:1678-1687; ; Voss M., et al. (2009) BMC Immunol. 10:53-53

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Immunology

NP_000630

P48023

Human

MGSSHHHHHH SSGLVPRGSH MQIGHPSPPP EKKELRKVAH LTGKSNSRSM PLEWEDTYGI VLLSGVKYKK GGLVINETGL YFVYSKVYFR GQSCNNLPLS HKVYMRNSKY PQDLVMMEGK MMSYCTTGQM WARSSYLGAV FNLTSADHLY VNVSELSLVN FEESQTFFGL YKL