Recombinant humaan Fc epsilon RI alfa/FCER1A eiwit
Gecertificeerd

Recombinant humaan Fc epsilon RI alfa/FCER1A eiwit

Catalog #: ATGP2394-020
Maat: 20 µg

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

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Gratis verzending vanaf €100

Technische Specificaties

Description

The immunoglobulin epsilon receptor (IgE receptor) is the initiator of the allergic response. When two or more high-affinity IgE receptors are brought together by allergen-bound IgE molecules, mediators such as histamine that are responsible for allergy symptoms are released. This receptor is comprised of an alpha subunit, a beta subunit, and two gamma subunits. FCER1A represents the alpha subunit. Recombinant human FCER1A protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Name Alternative

High affinity immunoglobulin epsilon receptor subunit alpha, Fc-epsilon RI-alpha, FcepsilonRI alpha chain, FcERI, IgE Fc receptor subunit alpha, FCER1A, FCE1A

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

23.4 kDa (203aa) confirmed by MALDI-TOF

Additionnal Information

Fc epsilon RI a, high affinity immunoglobulin epsilon receptor subunit alpha precursor, high affinity immunoglobulin epsilon receptor subunit alpha precursor, FCE1A, FcERI, ATGP2394-10 µg, ATGP2394-20 µg, ATGP2394-50 µg, ATGP2394-100 µg, ATGP2394-250 µg, ATGP2394-500 µg, ATGP2394-1 mg, ATGP2394-10, ATGP2394-20, ATGP2394-50, ATGP2394-100, ATGP2394-250, ATGP2394-500, ATGP2394-1

References & Citations

ZHANG, Y., et al. (2012) Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 47 (4), 289-293; ; Zhou, J., et al. (2012) Hum. Immunol. 73 (3), 301-305;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 30% glycerol, 1mM DTT

Scientific Category

Immunology

NCBI Accession Number

NP_001992.1

Uniprot Accession Number

P12319

Species

Human

AA Sequence

VPQKPKV SLNPPWNRIF KGENVTLTCN GNNFFEVSST KWFHNGSLSE ETNSSLNIVN AKFEDSGEYK CQHQQVNESE PVYLEVFSDW LLLQASAEVV MEGQPLFLRC HGWRNWDVYK VIYYKDGEAL KYWYENHNIS ITNATVEDSG TYYCTGKVWQ LDYESEPLNI TVIKAPREKY WLQ

Beschrijving

The immunoglobulin epsilon receptor (IgE receptor) is the initiator of the allergic response. When two or more high-affinity IgE receptors are brought together

Specificaties

ProductnaamRecombinant humaan Fc epsilon RI alfa/FCER1A eiwit
Categorie
Beschikbare grootte20 µg
CatalogusnummerATGP2394-020