
Recombinant humaan Fc epsilon RI alfa/FCER1A eiwit
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
The immunoglobulin epsilon receptor (IgE receptor) is the initiator of the allergic response. When two or more high-affinity IgE receptors are brought together by allergen-bound IgE molecules, mediators such as histamine that are responsible for allergy symptoms are released. This receptor is comprised of an alpha subunit, a beta subunit, and two gamma subunits. FCER1A represents the alpha subunit. Recombinant human FCER1A protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
High affinity immunoglobulin epsilon receptor subunit alpha, Fc-epsilon RI-alpha, FcepsilonRI alpha chain, FcERI, IgE Fc receptor subunit alpha, FCER1A, FCE1A
E.coli
Human
His-Tag
SDS-PAGE
0.25 mg/mL (determined by Bradford assay)
> 85% by SDS-PAGE
23.4 kDa (203aa) confirmed by MALDI-TOF
Fc epsilon RI a, high affinity immunoglobulin epsilon receptor subunit alpha precursor, high affinity immunoglobulin epsilon receptor subunit alpha precursor, FCE1A, FcERI, ATGP2394-10 µg, ATGP2394-20 µg, ATGP2394-50 µg, ATGP2394-100 µg, ATGP2394-250 µg, ATGP2394-500 µg, ATGP2394-1 mg, ATGP2394-10, ATGP2394-20, ATGP2394-50, ATGP2394-100, ATGP2394-250, ATGP2394-500, ATGP2394-1
ZHANG, Y., et al. (2012) Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 47 (4), 289-293; ; Zhou, J., et al. (2012) Hum. Immunol. 73 (3), 301-305;
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 30% glycerol, 1mM DTT
Immunology
NP_001992.1
P12319
Human
VPQKPKV SLNPPWNRIF KGENVTLTCN GNNFFEVSST KWFHNGSLSE ETNSSLNIVN AKFEDSGEYK CQHQQVNESE PVYLEVFSDW LLLQASAEVV MEGQPLFLRC HGWRNWDVYK VIYYKDGEAL KYWYENHNIS ITNATVEDSG TYYCTGKVWQ LDYESEPLNI TVIKAPREKY WLQ
Beschrijving
The immunoglobulin epsilon receptor (IgE receptor) is the initiator of the allergic response. When two or more high-affinity IgE receptors are brought together
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