Recombinant humaan FGF-14-eiwit

FGF14 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. A mutation in this gene is associated with autosomal dominant cerebral ataxia. Alternatively spliced transcript variants have been found for this gene. Recombinant human FGF14 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Fibroblast growth factor 14 isoform 1A, FGF-14, FHF-4, FHF4, SCA27

E.coli

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

30kDa (271aa) confirmed by MALDI-TOF

FGF 14, FGF14, Fibroblast growth factor 14 isoform 1A, FGF-14, FHF-4, FHF 4, FHF4, SCA27, ATGP2128-10 µg, ATGP2128-20 µg, ATGP2128-50 µg, ATGP2128-100 µg, ATGP2128-250 µg, ATGP2128-500 µg, ATGP2128-1 mg, ATGP2128-010, ATGP2128-020, ATGP2128-050, ATGP2128-100, ATGP2128-250, ATGP2128-500, ATGP2128-01M

Smallwood PM, et al. (1996) . Proc Natl Acad Sci u S A. 93 (18) :9850-7.; ; Wozniak DF, Xiao M, Xu L, et al. (2007) . Neurobiol Dis. 26 (1) :14-26.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 50% glycerol, 5mM DTT

Hormones & Cytokines

NP_004106

Q92915

Human

MGSSHHHHHH SSGLVPRGSH MGSHMAAAIA SGLIRQKRQA REQHWDRPSA SRRRSSPSKN RGLCNGNLVD IFSKVRIFGL KKRRLRRQDP QLKGIVTRLY CRQGYYLQMH PDGALDGTKD DSTNSTLFNL IPVGLRVVAI QGVKTGLYIA MNGEGYLYPS ELFTPECKFK ESVFENYYVI YSSMLYRQQE SGRAWFLGLN KEGQAMKGNR VKKTKPAAHF LPKPLEVAMY REPSLHDVGE TVPKPGVTPS KSTSASAIMN GGKPVNKSKT T