Recombinant humaan FGF R2 alfa-eiwit

FGFR2, also known as fibroblast growth factor receptor 2 isoform 2, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. It plays an important regulatory role in skeletal development and bone formation. Its dysregulation results in a spectrum of bone and skin pathologies and several types of cancer. Recombinant human FGFR2, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Fibroblast growth factor receptor 2 isoform 2, FGFR2, BBDS, BEK, BFR-1, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25

Baculovirus

Human

HIgG-His-Tag

SDS-PAGE

1 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 95% by SDS-PAGE

66.6 kDa (596aa)

FGF R2 a, Fibroblast growth factor receptor 2 isoform 2, FGFR2, BBDS, BEK, BFR-1, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25, ATGP3621-10 µg, ATGP3621-20 µg, ATGP3621-50 µg, ATGP3621-100 µg, ATGP3621-250 µg, ATGP3621-500 µg, ATGP3621-1 mg, ATGP3621-10, ATGP3621-20, ATGP3621-50, ATGP3621-100, ATGP3621-250, ATGP3621-500, ATGP3621-1

Kaabeche K., et al. (2004) J Biol Chem. 279:36259-36267.; ; Katoh M., et al. (2009) J Invest Dermatol. 129:1861-1867.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Cardiovascular

NP_075259

P21802

Human

Arg22